Talaromyces spp. infections in dogs from the Southern United States

Vet Pathol. 2022 May;59(3):451-454. doi: 10.1177/03009858221075589. Epub 2022 Feb 9.


Talaromyces spp. are soil-dwelling fungi sporadically reported to cause disease in humans and dogs. This study summarized the clinical presentations, histologic findings, and Talaromyces sp. involved in 5 dogs diagnosed through the panfungal polymerase chain reaction service (PCR) at Texas A&M University, with a review of previously reported cases. Of the 5 cases, 3 were Labrador Retrievers, 2 were male, and 3 were female. Three of 5 involved the musculoskeletal or lymphatic systems, and 2 of 5 dogs presented with meningoencephalitis. Talaromyces helicus, Talaromyces aurantiacus, and Talaromyces boninensis were identified based on panfungal PCR, showing 99% to 100% sequence matches in combination with morphologic features. Three of 5 dogs had static disease at the time of publication, 1 was euthanized, and 1 was lost to follow-up. This study describes Talaromyces spp. as a cause of meningoencephalitis in dogs, identifies 2 novel Talaromyces spp. involved in infections, and adds to the existing knowledge of clinical presentations and outcomes.

Keywords: fungi; meningoencephalitis; mycoses; panfungal polymerase chain reaction; pathology.

MeSH terms

  • Animals
  • Dog Diseases* / diagnosis
  • Dog Diseases* / epidemiology
  • Dog Diseases* / microbiology
  • Dogs
  • Female
  • Male
  • Meningoencephalitis* / veterinary
  • Mycoses* / epidemiology
  • Mycoses* / microbiology
  • Mycoses* / veterinary
  • Polymerase Chain Reaction / veterinary
  • Talaromyces*
  • United States

Supplementary concepts

  • talaromycosis