Environmental integrons: the dark side of the integron world

Eva Sandoval-Quintana; Béatrice Lauga; Christine Cagnon

doi:10.1016/j.tim.2022.01.009

Environmental integrons: the dark side of the integron world

Trends Microbiol. 2023 May;31(5):432-434. doi: 10.1016/j.tim.2022.01.009. Epub 2022 Feb 7.

Authors

Eva Sandoval-Quintana¹, Béatrice Lauga², Christine Cagnon³

Affiliations

¹ Universite de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, Pau, France.
² Universite de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, Pau, France. Electronic address: beatrice.lauga@univ-pau.fr.
³ Universite de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, Pau, France. Electronic address: christine.cagnon@univ-pau.fr.

PMID: 35140037
DOI: 10.1016/j.tim.2022.01.009

Abstract

Integrons are bacterial genetic elements notorious for their role in spreading antibiotic resistance in clinical settings. In the natural environment, integrons present a wide and hidden diversity, raising questions as to their broader role in bacterial adaptation. From the One Health perspective, they must be considered a threatening pool of resistance determinants.

Keywords: One Health; bacterial adaptation; dispersal; genetic rearrangement; integrons; microbial communities.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology
Bacteria* / drug effects
Bacteria* / genetics
Drug Resistance, Bacterial* / genetics
Integrons* / genetics

Substances

Anti-Bacterial Agents