Are fructophilic lactic acid bacteria (FLAB) beneficial to humans?

Benef Microbes. 2022 Feb 28;13(1):3-11. doi: 10.3920/BM2021.0044. Epub 2022 Feb 11.


Fructophilic lactic acid bacteria (FLAB) are heterofermentative and related to the genera Fructilactobacillus, Convivina, Leuconostoc, Oenococcus and Weissella. Although they generally prefer fructose above glucose, obligate heterofermentative species will ferment glucose in the presence of external electron acceptors such as pyruvate and fructose. Little is known about the presence of FLAB in the human gut, let alone probiotic properties. In this review we discuss the possible role FLAB may have in the human gastro-intestinal tract (GIT) and highlight the advantages and disadvantages these bacteria may have in individuals with a diet high in fructose.

Keywords: advantages; disadvantages; fructophilic lactic acid bacteria; human health.

Publication types

  • Review

MeSH terms

  • Fermentation
  • Fructose
  • Glucose
  • Humans
  • Lactobacillales*
  • Probiotics*


  • Fructose
  • Glucose