In recent years, the number of diabetic patients has gradually increased, and the number of patients with diabetic foot has also increased. Diabetic foot has a high rate of disability and death, seriously affects the patients' quality of life, shortens life expectancy, and brings heavy social burden. The current treatment methods for diabetic foot are insufficient. The concepts and methods of tissue engineering provide new thoughts and means for the treatment of diabetic foot. This article introduces the pathogenesis of diabetic foot wounds, the factors leading to non-healing of diabetic foot, the applications of functional hydrogel dressings in the treatment of diabetic foot and their technical methods of functional hydrogel dressings for treating skin wounds in diabetic animals, and the future development direction of functional hydrogel dressing for treating diabetic foot wounds is prospected.
近年来，糖尿病患者人数逐渐增加，发生糖尿病足患者人数也随之增加。糖尿病足具有较高的致残率和致死率，严重影响患者的生活质量，既缩短预期寿命，又带来沉重的社会负担。糖尿病足目前的治疗方法存在不足，组织工程的理念与方法为糖尿病足的治疗提供了新的思路和手段。本文介绍了糖尿病足的发病机制、导致糖尿病足创面难愈合的因素、用于治疗糖尿病足创面的功能性水凝胶敷料，以及功能性水凝胶敷料用于治疗糖尿病动物皮肤创面的技术方法，并对治疗糖尿病足创面的功能性水凝胶敷料未来发展方向进行了展望。.