An Unusual Presentation of Diffuse Large B-Cell Lymphoma

Cureus. 2022 Jan 4;14(1):e20927. doi: 10.7759/cureus.20927. eCollection 2022 Jan.

Abstract

Hyperlactemia is a rare and potentially fatal complication of hematologic malignancies, as well as an oncological emergency, which requires a fast diagnosis and early therapeutic management, as these interventions may alter disease prognosis. Herein, we present a case of secondary liver-biopsy-confirmed diffuse large B-cell lymphoma (DLBCL), presented with elevated liver enzymes and lactic acidosis, without depicted hepatic lesions, hepatosplenomegaly, or enlarged lymph nodes on computed tomography. This case confirms the poor prognosis of cases with delayed diagnostic intervention and highlights the importance of early clinical suspicion, liver biopsy, and prompt treatment initiation.

Keywords: diffuse large b-cell lymphoma; lactic acidosis; liver biopsy; liver infiltration; liver lymphoma.

Publication types

  • Case Reports