Adult-onset Still's disease (AOSD) is a disorder that is occasionally seen. Autoinflammation is a generally accepted pathogenic mechanism leading to systemic signs and symptoms. We report the case of a young female presenting with high-grade fever, rash, and arthralgias. After a thorough assessment, the diagnosis of adult-onset Still's disease was made based on presenting symptoms and elevated serum ferritin, c-reactive protein (CRP), and absence of serologic markers and confirmed based on Yamaguchi criteria. She was treated with corticosteroids and achieved complete clinical remission.
Keywords: adult onset stills disease; autoinflammation; negative serological markers; steroids; yamaguchi criteria.
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