Negative effect of Metoclopramide in postoperative adynamic ileus. A prospective, randomized, double blind study

Br J Surg. 1986 Apr;73(4):290-1. doi: 10.1002/bjs.1800730414.


In a double blind controlled study including 60 patients it was found that Metoclopramide has a negative effect upon the resolution of postoperative adynamic ileus. Metoclopramide causes a delay in the time from operation to the first passage of flatus.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Flatulence
  • Humans
  • Intestinal Obstruction / drug therapy*
  • Male
  • Metoclopramide / therapeutic use*
  • Middle Aged
  • Postoperative Complications / drug therapy*
  • Prospective Studies
  • Random Allocation
  • Time Factors


  • Metoclopramide