Sarcopenia in Chronic Pancreatitis - Prevalence, Diagnosis, Mechanisms and Potential Therapies

Matthew Fasullo; Endashaw Omer; Matthew Kaspar

doi:10.1007/s11894-022-00837-6

Sarcopenia in Chronic Pancreatitis - Prevalence, Diagnosis, Mechanisms and Potential Therapies

Curr Gastroenterol Rep. 2022 Apr;24(4):53-63. doi: 10.1007/s11894-022-00837-6.

Authors

Matthew Fasullo¹, Endashaw Omer², Matthew Kaspar³

Affiliations

¹ Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University (VCU), Richmond, VA, USA.
² Division of Gastroenterology, Hepatology, and Nutrition, University of Louisville, Louisville, KY, USA.
³ Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University (VCU), Richmond, VA, USA. matthew.kaspar@vcuhealth.org.

PMID: 35167003
DOI: 10.1007/s11894-022-00837-6

Abstract

Purpose of review: To investigate the prevalence, pathogenesis, diagnosis, clinical sequelae, and management of sarcopenia to improve mortality and quality of life in those with Chronic Pancreatitis.

Recent findings: Sarcopenia is prevalent in chronic pancreatitis and can significantly affect clinical outcomes. Sarcopenia is prevalent in chronic pancreatitis. While effects on some clinical outcomes is has been shown, there is a significant gap in knowledge regarding effects on outcomes, pathophysiology, and options for management.

Keywords: Chronic pancreatitis; Malnutrition; Pancreatitis; Sarcopenia.

Publication types

Review

MeSH terms

Disease Progression
Humans
Malnutrition* / etiology
Pancreatitis, Chronic* / complications
Pancreatitis, Chronic* / diagnosis
Pancreatitis, Chronic* / epidemiology
Prevalence
Quality of Life
Sarcopenia* / diagnosis
Sarcopenia* / epidemiology
Sarcopenia* / etiology