Development and evaluation of an exome sequencing training course for medical interpreters

Per Med. 2022 Mar;19(2):125-138. doi: 10.2217/pme-2021-0091. Epub 2022 Feb 16.


Aim: As genomic medicine reaches more diverse populations, there is an increased need for healthcare interpreters who understand and can effectively interpret genomics concepts. Methods: We designed a course for healthcare interpreters on exome sequencing to enhance their preparedness for genomic results disclosure appointments in the Cancer Health Assessments Reaching Many (CHARM) study and beyond. The course was evaluated via pre/post surveys and qualitative interviews. Results: 23 interpreters completed the course; 87% rated it as excellent/very good. Improved pre/post confidence interpreting for genetics appointments was statistically significant; pre/post knowledge was not. Interviews highlighted the need for more discussion time. Conclusion: While the course increased confidence interpreting for exome sequencing results appointments, suggested modifications could enhance knowledge and retention of key concepts.

Keywords: Spanish–English interpreters; exome sequencing; genomics; genomics education; health disparities; health equity; healthcare interpreters; interpreter-mediated consultation; limited English proficiency; medical interpreters.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Exome / genetics
  • Exome Sequencing
  • Genomics
  • Humans
  • Physician-Patient Relations*
  • Translating*