Case 5-2022: A 65-Year-Old Woman with Rapidly Progressive Weakness in the Right Arm and Recurrent Falls

N Engl J Med. 2022 Feb 17;386(7):674-687. doi: 10.1056/NEJMcpc2115852.

Authors

Christopher D Stephen¹, Pamela W Schaefer¹, Brian S Appleby¹, Derek H Oakley¹

Affiliation

¹ From the Departments of Neurology (C.D.S.), Radiology (P.W.S.), and Pathology (D.H.O.), Massachusetts General Hospital, and the Departments of Neurology (C.D.S.), Radiology (P.W.S.), and Pathology (D.H.O.), Harvard Medical School - both in Boston; and the Department of Neurology, National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland (B.S.A.).

PMID: 35172059
DOI: 10.1056/NEJMcpc2115852

No abstract available

Publication types

Case Reports
Clinical Conference

MeSH terms

Accidental Falls*
Aged
Brain / pathology*
Creutzfeldt-Jakob Syndrome / complications
Creutzfeldt-Jakob Syndrome / diagnosis
Creutzfeldt-Jakob Syndrome / genetics*
Diagnosis, Differential
Family
Fatal Outcome
Female
Genetic Counseling
Humans
Magnetic Resonance Imaging
Muscle Weakness / etiology*
Muscle Weakness / genetics
Mutation
Prion Proteins / genetics*

Substances

PRNP protein, human
Prion Proteins