A less painful transfer of power

Neuron. 2022 Feb 16;110(4):559-561. doi: 10.1016/j.neuron.2022.01.021.

Abstract

Transfer between cells is an unexpected addition to the mitochondrial life cycle. In this issue of Neuron, Van der Vlist et al. now provide evidence that M2-macrophages infiltrating sensory ganglia resolve pain by transferring particles containing mitochondria to neurons-thus boosting nociceptors back to normal function.

Publication types

  • Comment

MeSH terms

  • Ganglia, Spinal* / cytology
  • Humans
  • Mitochondria
  • Neurons
  • Nociceptors* / metabolism
  • Pain / physiopathology