Lasers, lights, and compounds for hair loss in aesthetics

Clin Dermatol. 2022 Jan-Feb;40(1):64-75. doi: 10.1016/j.clindermatol.2021.08.013. Epub 2021 Aug 8.


Hair loss is a common complaint that is often stressful for patients and a challenge for practitioners to treat. Fortunately, innovations in the field have contributed to growing evidence for several promising topical, oral, and light and energy-based therapies. We have reviewed the current literature about the efficacy of these treatments, including topical agents (finasteride, latanoprost, spironolactone, caffeine, and metformin), oral minoxidil, nutraceuticals, platelet-rich plasma, low-level laser therapy, fractional lasers, and laser-assisted drug delivery. In addition, several debates related to these treatments have been discussed, including post-finasteride syndrome, effects of biotin supplementation on laboratory testing, standardization of platelet-rich plasma and low-level laser therapy, and combination treatment to enhance hair transplantation.

MeSH terms

  • Alopecia* / drug therapy
  • Esthetics
  • Finasteride / therapeutic use
  • Humans
  • Lasers
  • Minoxidil* / therapeutic use
  • Treatment Outcome


  • Finasteride
  • Minoxidil