Acute Kidney Injury in Patients With Cancer: A Review of Onconephrology

Adv Chronic Kidney Dis. 2021 Sep;28(5):394-401.e1. doi: 10.1053/j.ackd.2021.09.008.

Abstract

Over the past 2 decades, significant research and advancements have been made in oncology and its therapeutics. Thanks to novel diagnostic methods, treatments, and supportive measures, patients with cancer live longer and have a better quality of life. However, an unforeseen consequence of this progress has been increasing medical complications, including acute kidney injury. The purpose of this review is to provide an overview of the epidemiology and most common causes of acute kidney injury in patients with cancer unrelated to oncological treatment.

Keywords: Acute kidney injury (AKI); Hematopoietic stem cell transplant (HSCT); Kidney replacement therapy (KRT); Thrombotic microangiopathy (TMA); Tumor lysis syndrome (TLS).

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury* / epidemiology
  • Acute Kidney Injury* / etiology
  • Acute Kidney Injury* / therapy
  • Hematopoietic Stem Cell Transplantation* / adverse effects
  • Hematopoietic Stem Cell Transplantation* / methods
  • Humans
  • Neoplasms* / complications
  • Neoplasms* / epidemiology
  • Neoplasms* / therapy
  • Quality of Life
  • Thrombotic Microangiopathies* / etiology