Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity

Carolina Nicolela Susanna; Bianca Nicolela Susanna; Fernanda Nicolela Susanna; Remo Susanna Jr; Carlos Gustavo De Moraes

doi:10.18502/jovr.v17i1.10167

Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity

J Ophthalmic Vis Res. 2022 Jan 21;17(1):27-32. doi: 10.18502/jovr.v17i1.10167. eCollection 2022 Jan-Mar.

Authors

Carolina Nicolela Susanna¹, Bianca Nicolela Susanna¹, Fernanda Nicolela Susanna², Remo Susanna Jr², Carlos Gustavo De Moraes³

Affiliations

¹ Department of Ophthalmology, ABC Foundation School of Medicine, Santo André, Brazil.
² Department of Ophthalmology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
³ Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.

Abstract

Purpose: To investigate the association between the time of occurrence of intraocular pressure (IOP) peaks during the water-drinking test (WDT) and visual field damage in a cohort of primary open-angle glaucoma (POAG) patients.

Methods: In this retrospective, cross-sectional study, 98 eyes from 49 consecutive POAG patients were followed in a referral clinical practice. The relationship between the time when IOP peaks occurred during the WDT and the visual field mean deviation (MD) assessed with 24-2 visual field was tested with mixed-effects models.

Results: MD value was significantly associated with the time of IOP peak occurrence (P = 0.020) when adjusting for the number of medications, but not with the IOP peak values (P = 0.238).

Conclusion: The time of IOP peaks occurrence during the WDT was associated with glaucoma severity among treated POAG patients.

Keywords: IOP Peak Time; Primary Open-angle Glaucoma; Water Drinking Test; Glaucoma Severity.