Bonded amalgam as a fissure sealant in low-income setting: A randomised controlled trial

J Pak Med Assoc. 2022 Feb;72(Suppl 1)(2):S3-S9. doi: 10.47391/JPMA.AKU-02.


Objectives: To compare one year retention rate of bonded amalgam sealants (BAS) with that of conventional resin-based sealant (RBS).

Methods: It was a parallel group, equivalence, randomised controlled trial done during March 2018 to December 2019 at the dental clinics of Dow University of Health Sciences, and the Jinnah Sind Medical University, Karachi, Pakistan on children aged 12-16 years, who were randomly assigned to one of the two treatment groups (BAS vs. RBS). Complete retention of the sealant at one year follow-up was labeled as success. Multi-level mixed effect logistic regression model was employed. Study was registered at # NCT NCT03130725.

Results: There were 137 teeth (23 subjects) in the BAS and 128 teeth (15 subjects) in the RBS group that were evaluated for sealant retention at 12 months follow-up. Among the BAS group, 100/137 (73%) sealants were completely retained whereas 110/128 (86%) were fully retained in the RBS group. Nearly, 22/137 (16%) BAS and 10/128 (7.8%) RBS were completely dislodged. In multivariable analysis, subject age >15 years and male gender were found to be significantly associated with the dislodgement of sealants.

Conclusions: At 12 months follow-up, the retention of bonded amalgam sealant (BAS) was significantly lower than that of the resin-based sealant (RBS).

Rct registration: with # NCT NCT03130725.

Keywords: Bonded amalgam sealants, Resin-based sealants, Retention, Caries..

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Child
  • Dental Caries*
  • Humans
  • Logistic Models
  • Male
  • Pakistan
  • Pit and Fissure Sealants* / therapeutic use
  • Poverty


  • Pit and Fissure Sealants

Associated data