Prevention of Necrotizing Enterocolitis

Clin Perinatol. 2022 Mar;49(1):195-206. doi: 10.1016/j.clp.2021.11.012. Epub 2022 Jan 21.


Necrotizing enterocolitis (NEC) is considered to be one of the most devastating intestinal diseases seen in neonatal intensive care. Measures to treat NEC are often too late, and we need effective preventative measures to alleviate the burden of this disease. The purpose of this review is to summarize currently used measures, and those showing future promise for prevention.

Keywords: Gestational age; Necrotizing enterocolitis; Neonatal; Preterm.

Publication types

  • Review

MeSH terms

  • Enterocolitis, Necrotizing* / prevention & control
  • Female
  • Fetal Diseases*
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases*
  • Infant, Premature
  • Intensive Care, Neonatal