Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy

Inflamm Bowel Dis. 2022 Feb 25;izac028. doi: 10.1093/ibd/izac028. Online ahead of print.
No abstract available

Keywords: inflammatory bowel disease; sperm DNA integrity; ustekinumab.

Plain language summary

We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.