Foreign-body giant cell reaction to liquid silicone

Am J Ophthalmol. 1986 Jun 15;101(6):680-3. doi: 10.1016/0002-9394(86)90768-3.


Although intravitreal injections of liquid silicone have long been used in complicated retinal detachments and long-term complications such as keratopathy, glaucoma, and cataract are well-known, the effect of liquid silicone on the retina, iris, and angle structures is not as well defined. Histopathologic study of one human eye that was enucleated 20 months after liquid silicone injection showed an intraocular foreign-body giant cell reaction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anterior Eye Segment / pathology*
  • Eye Diseases / etiology
  • Eye Diseases / pathology
  • Foreign-Body Reaction / etiology*
  • Foreign-Body Reaction / pathology
  • Humans
  • Injections
  • Male
  • Retina / pathology
  • Silicones / adverse effects*
  • Vacuoles / pathology
  • Vitreous Body


  • Silicones