doi: 10.1111/aor.14203.
Epub 2022 Feb 28.
First successful porcine to human heart transplantation performed in the United States
- PMID: 35224761
- DOI: 10.1111/aor.14203
Item in Clipboard
First successful porcine to human heart transplantation performed in the United States
Artif Organs.
2022 Apr.
Abstract
In an 8-h operation, the cardiac surgery team at the University of Maryland Medical Center made history by performing the first porcine-to-human heart transplant without signs of early rejection. Xenotransplantation offers a potential solution to the thousands of patients worldwide who die annually while waiting for donor organs.
© 2022 International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.
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References
FURTHER READING
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- Mohiuddin M, Goerlich C, Singh A, Zhang T, Tatarov I, Lewis B, et al. Progressive genetic modifications with growth hormone receptor knockout extends cardiac Xenograft survival to 9 months. Res Sq. 2021;Preprint.
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- Cooley DA, Hallman GL, Bloodwell RD, Nora JJ, Leachman RD. Human heart transplantation. Experience with twelve cases. Am J Cardiol. 1968;22(6):804-10.
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- Cooper DKC. Genetically engineered pig kidney transplantation in a brain-dead human subject. Xenotransplantation. 2021;28(6):e12718.
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- Mohiuddin MM, Singh AK, Corcoran PC, Thomas Iii ML, Clark T, Lewis BG, et al. Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft. Nat Commun. 2016;7:11138.
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- OPTN. National data. Available from: https://optn.transplant.hrsa.gov/data/view-data-reports/national-data/#
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