Human leukocyte interferon in the treatment of varicella in children with cancer: a preliminary controlled trial

Antimicrob Agents Chemother. 1978 Apr;13(4):605-7. doi: 10.1128/AAC.13.4.605.

Abstract

Eighteen patients who developed varicella while being treated for malignancy received human leukocyte interferon in a randomized double-blind placebo-controlled trial. Complications of varicella occurred in six of nine placebo recipients, but in only two of nine interferon recipients. Interferon was tolerated without significant side effects.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blood Cell Count
  • Chickenpox / complications
  • Chickenpox / drug therapy*
  • Chickenpox / microbiology
  • Child
  • Clinical Trials as Topic
  • Humans
  • Interferons / adverse effects
  • Interferons / therapeutic use*
  • Leukocytes / physiology*
  • Neoplasms / complications*
  • Placebos

Substances

  • Placebos
  • Interferons