Unusual Presentation of Skin Tattoo-Associated Panuveitis

Ocul Immunol Inflamm. 2023 Apr;31(3):653-655. doi: 10.1080/09273948.2022.2042322. Epub 2022 Feb 28.

Abstract

Aim: We report a case of a young male who developed bilateral panuveitis after extensive tattooing.

Design: Case report.

Methods: A 22-year-old male with a history of inflamed tattoos presented with pain in both eyes and blurred vision in the left eye. Clinical examination showed ciliary congestion, flare, vitreous cells in both eyes, and posterior synechiae in the left eye. Optic nerve was swollen in both eyes. OCT scans demonstrated subretinal blood, associated with neurosensory macular detachment in the left eye. The skin tattoo biopsy showed a granulomatous inflammation without evidence of sarcoidosis. Long-term corticosteroid therapy allowed a regression of clinical signs and symptoms with full recovery.

Conclusion: TAttoo Granulomas with Uveitis (TAGU) is a syndrome with numerous clinical presentations. In our case, optic nerve head oedema and subretinal hemorrhage at the posterior pole were the presentation signs. Ophthalmologists should always consider TAGU as a diagnosis in patients with a history of inflamed tattoos.

Keywords: TAttoo Granulomas with Uveitis (TAGU); Tattoo; corticosteroid therapy; optic disc oedema; panuveitis; subretinal hemorrhage; uveitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Granuloma / complications
  • Humans
  • Male
  • Panuveitis* / diagnosis
  • Panuveitis* / drug therapy
  • Panuveitis* / etiology
  • Sarcoidosis* / diagnosis
  • Skin / pathology
  • Tattooing* / adverse effects
  • Uveitis* / complications
  • Young Adult