Genetic polymorphism of mephenytoin metabolism

Prog Clin Biol Res. 1986:214:139-56.
No abstract available

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Chemical Phenomena
  • Chemistry
  • China / ethnology
  • Cytochrome P-450 CYP2C19
  • Debrisoquin / metabolism
  • Dogs
  • Ethnicity
  • Humans
  • Hydantoins / metabolism*
  • Hydroxylation
  • Japan / ethnology
  • Kinetics
  • Liver / metabolism
  • Mephenytoin / analogs & derivatives
  • Mephenytoin / metabolism*
  • Mephobarbital / metabolism
  • Mice
  • Mixed Function Oxygenases / metabolism
  • Ontario
  • Phenotype
  • Polymorphism, Genetic
  • Sparteine / metabolism
  • Tennessee
  • White People

Substances

  • Hydantoins
  • ethylphenylhydantoin
  • Sparteine
  • Mephobarbital
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Mephenytoin
  • Debrisoquin