Multiple endocrine neoplasia 2: an overview

B Saravana-Bawan; J D Pasternak

doi:10.1177/20406223221079246

Multiple endocrine neoplasia 2: an overview

Ther Adv Chronic Dis. 2022 Feb 25:13:20406223221079246. doi: 10.1177/20406223221079246. eCollection 2022.

Authors

B Saravana-Bawan¹, J D Pasternak²

Affiliations

¹ University Health Network, University of Toronto, Toronto, ON, Canada.
² Section Head, Endocrine Surgery and Oncology, Division of General Surgery, Sprott Department of Surgery, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada.

Abstract

This review article discusses the diagnosis and treatment of patients with multiple endocrine neoplasia type 2 (MEN2). The most common tumors associated with MEN2 are those of the parathyroid, thyroid, and adrenal glands. Additional manifestations include characteristic clinical phenotypes or features as described in the article. This review provides an overview of clinical manifestations, screening, diagnosis, treatment, and surveillance of patients with MEN2.

Keywords: MEN2; hyperparathyroidism; medullary thyroid cancer; multiple endocrine neoplasia; pheochromocytoma.

Publication types

Review