Non-adrenergic non-cholinergic nervous control of gastrointestinal motility patterns

Arch Int Pharmacodyn Ther. 1986 Apr;280(2 Suppl):50-61.


Non-adrenergic non-cholinergic neurons seem to play an important role in regulation of movements in all parts of the gut. Inhibitory non-adrenergic non-cholinergic neurons mediate a number of descending and ascending reflex effects of physiological and pathophysiological relevance. However, our knowledge in this field is still limited. Development of specific blockers for the non-adrenergic non-cholinergic transmitter substances would help to increase our understanding of gastrointestinal motor functions in health and disease.

Publication types

  • Review

MeSH terms

  • Animals
  • Autonomic Nervous System / physiology*
  • Dyspepsia / physiopathology
  • Esophagogastric Junction / physiology
  • Esophagus / physiology
  • Gastrointestinal Motility*
  • Humans
  • Intestinal Obstruction / physiopathology
  • Muscle Relaxation
  • Nausea / physiopathology
  • Peristalsis
  • Stomach / physiology
  • Vagotomy