Comparative study of treatment methods for benign lichenoid keratosis of the face

Dermatol Ther. 2022 May;35(5):e15419. doi: 10.1111/dth.15419. Epub 2022 Mar 12.


Benign lichenoid keratosis is one of the most common skin lesions that develop on the faces of middle-aged women. This study aimed to find an effective treatment method for benign lichenoid keratosis. A total of 49 patients, who had a positive diagnosis during 2010-2018, were enrolled in the study. An Investigator's Global Assessment of the lesion was done using the 5-point visual analog scale to evaluate treatment efficacy. After excluding subjects who did not have a follow-up photograph, 38 subjects were given an Investigator's Global Assessment score. Combination therapy using laser and a topical agent was useful in the management of benign lichenoid keratosis on the face. Ablative laser was effective for immediate improvement of the lesion, whereas non-ablative laser was also useful and showed several benefits over ablative laser. Optimal treatment should be decided after considering the patient's preference, compliance with treatment regimen, and skin type.

Keywords: benign lichenoid keratosis; comparative study.

MeSH terms

  • Acanthoma*
  • Combined Modality Therapy
  • Female
  • Humans
  • Keratosis, Actinic*
  • Light
  • Middle Aged
  • Skin Neoplasms* / pathology