Sensorineural hearing loss and ulcerative colitis in remission

Indian J Gastroenterol. 2022 Apr;41(2):143-148. doi: 10.1007/s12664-021-01216-1. Epub 2022 Mar 5.


Introduction: Sensorineural hearing loss (SNHL) has been reported in association with inflammatory bowel disease (IBD). However, SNHL as an extraintestinal manifestation of IBD is frequently underreported. In the present study, we compared the prevalence and severity of SNHL among patients with IBD-ulcerative colitis (IBD-UC) in remission with controls to find out any association between SNHL and IBD-UC in remission compared to controls.

Methods: This single-center hospital-based prospective observational study included outdoor patients with IBD-UC in remission and healthy age- and sex-matched controls. Eligible patients and healthy participants were subjected to a battery of audiological tests (otoscopy, tympanometry and pure tone audiometry [PTN]) after thorough systemic and ear, nose and throat (ENT) examination.

Results: A total of 100 patients were enrolled in the study: 50 in IBD-UC in the remission group and 50 in the control group. None of the demographic variables (age, gender, residence and habits) were significantly different between the two groups. Otoscopy and tympanometry were normal in all patients and controls. The difference between the two groups in respect to frequency and severity of SNHL on PTA and in respect to unilateral and bilateral distribution of the hearing loss was not statistically significant.

Conclusion: There is no statistically significant difference in frequency and severity of SNHL between patients with ulcerative colitis in remission and healthy age- and sex-matched controls.

Keywords: Autoimmune disease; Crohn disease; Extraintestinal manifestation; Inflammatory bowel disease; Mayo score; Montreal classification; Otoscopy; Pure tone audiometry; Sensorineural hearing loss; Tympanometry; Ulcerative colitis.

Publication types

  • Observational Study

MeSH terms

  • Audiometry, Pure-Tone
  • Colitis, Ulcerative* / complications
  • Colitis, Ulcerative* / epidemiology
  • Hearing Loss, Sensorineural* / diagnosis
  • Hearing Loss, Sensorineural* / epidemiology
  • Hearing Loss, Sensorineural* / etiology
  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Otoscopy