Uveitis intermedia as the initial presentation of a primary lymphoma of the central nervous system

Arch Soc Esp Oftalmol (Engl Ed). 2022 Mar;97(3):168-171. doi: 10.1016/j.oftale.2020.12.013. Epub 2021 Nov 17.


Primary central nervous system lymphoma is one of the most infrequent brain tumours, accounting for 3% of primary central nervous system neoplasms. In addition to its low prevalence, clinical presentation is usually nonspecific, leading to diagnostic delay. Intraocular involvement occurs in 15% of cases, and disease onset in this location is even rarer. We present a case of a patient with intermediate uveitis as the first clinical manifestation of this neoplasm.

Keywords: Intraocular methotrexate; Linfoma ocular; Linfoma primario del sistema nervioso central; Metotrexato intraocular; Ocular lymphoma; Primary central nervous system lymphoma; Uveitis intermediate; Uveítis intermedia.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms* / diagnostic imaging
  • Central Nervous System / pathology
  • Delayed Diagnosis
  • Humans
  • Lymphoma* / diagnostic imaging
  • Uveitis* / diagnosis