A novel glycosphingolipid that may participate in embryo inversion in Volvox carteri

Cell. 1986 Aug 15;46(4):633-9. doi: 10.1016/0092-8674(86)90889-5.

Abstract

Mouse monoclonal antibody 4-I-244 detects a developmentally regulated antigen in embryos of Volvox carteri and inhibits specifically the morphogenetic process of inversion (the process by which the embryo turns inside out). Antigen 4-I-244 was chemically characterized as a complex phytosphingolipid containing the neutral sugars xylose, galactose, and glucose as well as inositol and phosphate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal
  • Cell Membrane / immunology
  • Cell Membrane / physiology
  • Chlorophyta / immunology
  • Chlorophyta / physiology*
  • Chlorophyta / ultrastructure
  • Fluorescent Antibody Technique
  • Glycosphingolipids / analysis
  • Glycosphingolipids / immunology
  • Glycosphingolipids / physiology*
  • Morphogenesis

Substances

  • Antibodies, Monoclonal
  • Glycosphingolipids