Anti-viral triterpenes: a review

Phytochem Rev. 2022;21(6):1761-1842. doi: 10.1007/s11101-022-09808-1. Epub 2022 Mar 5.


Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic applications including anti-viral properties. In this review, the recent studies (2010-2020) concerning the anti-viral activities of triterpenes have been summarized. The structure activity relationship studies have been described as well as brief biosynthesis of these triterpenes is discussed.

Keywords: Anti-viral; Biosynthesis; Isoprenoid derivatives; Structure activity relationship; Triterpene.

Publication types

  • Review