A Rational Approach to Coagulation Testing

Lab Med. 2022 Jul 4;53(4):349-359. doi: 10.1093/labmed/lmac005.


Quality patient care requires the appropriate selection of laboratory tests. Irrelevant testing must be avoided, whereas pertinent testing is indispensable. The goals of this review are 3-fold: (1) to describe appropriate coagulation test selection for medical and surgical patients, (2) to describe appropriate coagulation testing specifically in individuals infected with SARS-CoV-2 causing COVID-19, and (3) to define the rational use of anticoagulant monitoring.

Keywords: activated partial thomboplastin time; coagulation; fibrinogen; platelet count; prothrombin time; test selection; viscoelastic testing.

Publication types

  • Review

MeSH terms

  • Blood Coagulation
  • Blood Coagulation Tests
  • COVID-19* / diagnosis
  • Humans
  • SARS-CoV-2*