1 Department of Cardiology, King's College Hospital London, Denmark Hill, Brixton, London, United Kingdom.
2 School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, James Black Centre, London, United Kingdom.
3 IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiovascular Network, Genova, Italy; and.
4 Department of Internal Medicine, University of Genova, Genova, Italy .