Cytoskeleton regulation: Distinct steps in Arp2/3 complex activation

Alexandra Colin; Laurent Blanchoin

doi:10.1016/j.cub.2022.01.071

Cytoskeleton regulation: Distinct steps in Arp2/3 complex activation

Curr Biol. 2022 Mar 14;32(5):R220-R222. doi: 10.1016/j.cub.2022.01.071.

Authors

Alexandra Colin¹, Laurent Blanchoin²

Affiliations

¹ CytoMorpho Lab, Laboratoire de Physiologie Cellulaire and Végétale, Interdisciplinary Research Institute of Grenoble, CEA/CNRS/Université Grenoble Alpes, Grenoble, France.
² CytoMorpho Lab, Laboratoire de Physiologie Cellulaire and Végétale, Interdisciplinary Research Institute of Grenoble, CEA/CNRS/Université Grenoble Alpes, Grenoble, France; CytoMorpho Lab, Unité de Thérapie Cellulaire, Hopital Saint Louis/CNRS/CEA, Paris, France. Electronic address: Laurent.blanchoin@cea.fr.

PMID: 35290770
DOI: 10.1016/j.cub.2022.01.071

Abstract

During branched actin assembly, several factors are necessary to activate the Arp2/3 complex. A new study reveals the importance of WASP- and actin-filament-mediated activation of the Arp2/3 complex in the assembly of functional actin networks.

Publication types

Comment

MeSH terms

Actin Cytoskeleton
Actin-Related Protein 2-3 Complex*
Actins*
Cytoskeleton
Microtubules

Substances

Actin-Related Protein 2-3 Complex
Actins