Ventricular tachycardia from myocarditis following COVID-19 vaccination with tozinameran (BNT162b2, Pfizer-BioNTech)

Pacing Clin Electrophysiol. 2022 Sep;45(9):1097-1100. doi: 10.1111/pace.14486. Epub 2022 Apr 4.

Abstract

To combat the coronavirus disease 2019 (COVID-19) pandemic, many countries have started population vaccination programs using messenger ribonucleic acid (mRNA) vaccines. With the widespread use of such vaccines, reports are emerging worldwide, of the vaccine's association with the development of myocarditis. Younger men are more likely to develop postvaccine myocarditis, which usually presents as self-limiting chest pain within a week after the second dose. We present a case of myocarditis following vaccination with tozinameran (BNT162b2, Pfizer-BioNTech), which presented late, with ventricular tachycardia (VT) reduced left ventricular ejection fraction (LVEF).

Keywords: COVID-19; acute myocarditis; mRNA vaccine; ventricular tachycardiac.

Publication types

  • Case Reports

MeSH terms

  • BNT162 Vaccine* / adverse effects
  • COVID-19* / prevention & control
  • Humans
  • Male
  • Myocarditis* / chemically induced
  • Myocarditis* / complications
  • Stroke Volume
  • Tachycardia, Ventricular* / etiology
  • Vaccination / adverse effects
  • Ventricular Function, Left

Substances

  • BNT162 Vaccine