A comparison of Kawasaki Disease and multisystem inflammatory syndrome in children

Philip A Wessels; Michael A Bingler

doi:10.1016/j.ppedcard.2022.101516

A comparison of Kawasaki Disease and multisystem inflammatory syndrome in children

Prog Pediatr Cardiol. 2022 Jun:65:101516. doi: 10.1016/j.ppedcard.2022.101516. Epub 2022 Mar 16.

Authors

Philip A Wessels¹, Michael A Bingler²

Affiliations

¹ Department of Pediatrics, Division of Residency, Nemours Children's Hospital, Orlando, FL, United States of America.
² Department of Cardiovascular Services, Division of Cardiology, Nemours Children's Hospital, Orlando, FL, United States of America.

Abstract

Background: Due to the COVID-19 pandemic a novel disease has emerged, multisystem inflammatory syndrome in children (MIS-C). It presents post virally after a COVID-19 infection, and its clinical presentation and symptoms are very similar to Kawasaki Disease (KD).

Aim of review: The objective of this review is to compare and contrast differences of Kawasaki Disease and MIS-C.

Key scientific concepts of the review: Kawasaki Disease and MIS-C are very similar in clinical presentation and symptomatology. Understanding the diagnostic criteria is crucial to making an accurate diagnosis. Treatments in Kawasaki Disease are established, while in MIS-C treatment protocols are continuing to develop. Careful history taking and laboratory marker analysis should guide the clinician to accurate diagnosis.

Keywords: COVID-19; Kawasaki Disease; Multisystem inflammatory syndrome in children.

Publication types

Review