Portal Vein Thrombosis and Pyogenic Liver Abscess With Concomitant Bacteroides Bacteremia in a Patient With COVID-19 Infection: A Case Report and Brief Review

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221084513. doi: 10.1177/23247096221084513.


The 2019 coronavirus disease (COVID-19) can present with a wide variety of clinical manifestations, including a hypercoagulable state leading to both arterial and venous thrombosis. Portal vein thrombosis (PVT) in the setting of COVID-19 has rarely been reported in the medical literature. Pylephlebitis with concomitant liver abscess is a rare complication of intra-abdominal infection. Here, we present the case of a 49-year-old man who initially presented with intermittent fevers and generalized weakness of 1-month duration and was subsequently found to have COVID-19 infection, PVT, and Bacteroides fragilis bacteremia with associated pyogenic liver abscess. The patient was treated with intravenous antibiotics and oral anticoagulation with plan to follow up outpatient with gastroenterology in 3 months to ensure resolution of PVT and liver abscess.

Keywords: gastroenterology; hematology oncology; infectious disease; pulmonary critical care.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bacteremia* / complications
  • Bacteremia* / drug therapy
  • Bacteroides
  • COVID-19* / complications
  • Humans
  • Liver Abscess, Pyogenic* / complications
  • Liver Abscess, Pyogenic* / diagnosis
  • Liver Abscess, Pyogenic* / drug therapy
  • Male
  • Middle Aged
  • Portal Vein
  • Venous Thrombosis* / complications
  • Venous Thrombosis* / drug therapy