Control of cell division in Escherichia coli. DNA sequence of dicA and of a second gene complementing mutation dicA1, dicC

Nucleic Acids Res. 1986 Sep 11;14(17):6821-33. doi: 10.1093/nar/14.17.6821.


A mutation in a gene dicA of Escherichia coli leads to temperature-sensitive cell division, by allowing expression of a nearby division inhibition gene dicB (1). We have now established the sequence of the DicA region and identified DicA as a 15.5 KD protein. A second gene dicC transcribed divergently from dicA and coding for an 8.5 KD protein can also complement mutation dicA1 when provided on a multicopy plasmid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Cell Division
  • Cloning, Molecular
  • Escherichia coli / genetics*
  • Genes, Bacterial*
  • Genetic Complementation Test
  • Mutation
  • Repressor Proteins / genetics
  • Temperature


  • Repressor Proteins

Associated data

  • GENBANK/X04395