The uses of tranexamic acid in dermatology: a review

Int J Dermatol. 2022 Mar 24. doi: 10.1111/ijd.16160. Online ahead of print.


Tranexamic acid is a plasmin inhibitor that is used off-label for the treatment of melasma. The use of tranexamic acid has expanded in the field of dermatology based on its anti-inflammatory and anti-melanin-producing properties, which include the treatment of rosacea, urticaria, and post-inflammatory hyperpigmentation. Tranexamic acid may have more uses in dermatology that require future studies. It should be used with caution during the COVID-19 pandemic given its procoagulant nature.

Publication types

  • Review