Post-fracture care programs for prevention of subsequent fragility fractures: a literature assessment of current trends

Osteoporos Int. 2022 Aug;33(8):1659-1676. doi: 10.1007/s00198-022-06358-2. Epub 2022 Mar 24.


Post-fracture care (PFC) programs evaluate and manage patients with a minimal trauma or fragility fracture to prevent subsequent fractures. We conducted a literature review to understand current trends in PFC publications, evaluate key characteristics of PFC programs, and assess their clinical effectiveness, geographic variations, and cost-effectiveness. We performed a search for peer-reviewed articles published between January 2003 and December 2020 listed in PubMed or Google Scholar. We categorized identified articles into 4 non-mutually exclusive PFC subtopics based on keywords and abstract content: PFC Types, PFC Effectiveness/Success, PFC Geography, and PFC Economics. The literature search identified 784 eligible articles. Most articles fit into multiple PFC subtopics (PFC Types, 597; PFC Effectiveness/Success, 579; PFC Geography, 255; and PFC Economics, 98). The number of publications describing how PFC programs can improve osteoporosis treatment rates has markedly increased since 2003; however, publication gaps remain, including low numbers of publications from some countries with reported high rates of osteoporosis and/or hip fractures. Fracture liaison services and geriatric/orthogeriatric services were the most common models of PFC programs, and both were shown to be cost-effective. We identified a need to expand and refine PFC programs and to standardize patient identification and reporting on quality improvement measures. Although there is an increasing awareness of the importance of PFC programs, publication gaps remain in most countries. Improvements in established PFC programs and implementation of new PFC programs are still needed to enhance equitable patient care to prevent occurrence of subsequent fractures.

Keywords: Care coordination; fracture liaison service; geriatric/orthogeriatric service; osteoporosis; post-fracture care.

Publication types

  • Review

MeSH terms

  • Aged
  • Cost-Benefit Analysis
  • Hip Fractures* / therapy
  • Humans
  • Osteoporosis* / drug therapy
  • Osteoporotic Fractures* / epidemiology
  • Quality Improvement
  • Secondary Prevention