Current Treatment of Myasthenia Gravis

J Clin Med. 2022 Mar 14;11(6):1597. doi: 10.3390/jcm11061597.

Abstract

Myasthenia gravis (MG) is the most extensively studied antibody-mediated disease in humans. Substantial progress has been made in the treatment of MG in the last century, resulting in a change of its natural course from a disease with poor prognosis with a high mortality rate in the early 20th century to a treatable condition with a large proportion of patients attaining very good disease control. This review summarizes the current treatment options for MG, including non-immunosuppressive and immunosuppressive treatments, as well as thymectomy and targeted immunomodulatory drugs.

Keywords: azathioprine; beta adrenergic; corticosteroids; cyclophosphamide; cyclosporine; eculizumab; efgartigimod; intravenous immunoglobulin; methotrexate; myasthenia gravis; plasma exchange; prednisone; pyridostigmine; stem cell transplant; tacrolimus; terbutaline.

Publication types

  • Review