Epidemic Reiter's syndrome following an outbreak of shigellosis

Eur J Epidemiol. 1986 Mar;2(1):26-30. doi: 10.1007/BF00152713.


We prospectively studied the occurrence of Reiter's syndrome (RS) or reactive arthritis (ReA) in 205 of 349 cruise-ship passengers who attended a buffet ashore and developed Shigella flexneri 2a enteritis. Five passengers probably had RS/ReA and 16 were possible or doubtful cases of RS/ReA. HLA-B27 was identified in 4 of 5 probable RS cases, but was not present in any of the 16 possible or doubtful cases nor in any of 20 passengers (controls) without any symptoms of RS/ReA. There was no statistically significant difference in the frequency of B7-Creg antigens in persons with possible or doubtful RS/ReA (9/16) compared to controls (8/20).

MeSH terms

  • Adult
  • Aged
  • Arthritis, Reactive / epidemiology*
  • Arthritis, Reactive / etiology
  • Disease Outbreaks / epidemiology*
  • Dominican Republic
  • Dysentery, Bacillary / complications
  • Dysentery, Bacillary / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prohibitins
  • Prospective Studies
  • Shigella flexneri
  • United States