Chitosan/PCL nanofibrous films developed by SBS to encapsulate thymol/HPβCD inclusion complexes for fruit packaging

Chaoyi Shen; Menglu Wu; Cui Sun; Jiangkuo Li; Di Wu; Chongde Sun; Yong He; Kunsong Chen

doi:10.1016/j.carbpol.2022.119267

Chitosan/PCL nanofibrous films developed by SBS to encapsulate thymol/HPβCD inclusion complexes for fruit packaging

Carbohydr Polym. 2022 Jun 15:286:119267. doi: 10.1016/j.carbpol.2022.119267. Epub 2022 Feb 21.

Authors

Chaoyi Shen¹, Menglu Wu², Cui Sun², Jiangkuo Li³, Di Wu⁴, Chongde Sun², Yong He⁵, Kunsong Chen²

Affiliations

¹ College of Biosystems Engineering and Food Science, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China; College of Agriculture & Biotechnology, Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China.
² College of Agriculture & Biotechnology, Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China.
³ Tianjin Academy of Agricultural Sciences, National Engineering and Technology Research Center for Preservation of Agricultural Products (Tianjin), Tianjin 300384, China.
⁴ College of Biosystems Engineering and Food Science, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China; College of Agriculture & Biotechnology, Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China; Zhejiang University Zhongyuan Institute, Zhengzhou 450000, PR China. Electronic address: di_wu@zju.edu.cn.
⁵ College of Biosystems Engineering and Food Science, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China.

PMID: 35337497
DOI: 10.1016/j.carbpol.2022.119267

Abstract

In this work, the solution blow spinning (SBS) technique was used to rapidly fabricate the thymol (THY)/2-hydroxypropyl-β-cyclodextrin (HPβCD) inclusion complexes loaded chitosan (CS)/polycaprolactone (PCL) nanofibrous films for fruit preservation and packaging. XRD results indicated that the THY/HPβCD inclusion complexes were successfully incorporated into the CS/PCL nanofibers. The nanofibrous films had an increase of average diameters of nanofibers from 243.84 nm to 560.55 nm, an enhancement of water vapor permeability, a decrease of the crystallinity, and a hydrophilic surface after the incorporation. FTIR and thermal analysis showed that the thermal stability was also improved due to the formation of hydrogen bonds between THY/HPβCD inclusion complexes and CS/PCL nanofibers. The developed films obtained a long-term continuous release of THY during 240 h, and had a good antifungal activity in vitro and in vivo. The above results indicated the promising prospects of SBS in developing antifungal nanofibrous films for postharvest fruit.

Keywords: 2-hydroxypropyl-β-cyclodextrin; Antifungal activity; Chitosan; Long-term continuous release; Self-assembly; Solution blow spinning.