Randomized, Controlled Trial of an Intervention Combining Self-Care and Self-Hypnosis on Fatigue, Sleep, and Emotional Distress in Posttreatment Cancer Patients: 1-Year Follow-Up

Int J Clin Exp Hypn. 2022 Apr-Jun;70(2):136-155. doi: 10.1080/00207144.2022.2049973. Epub 2022 Mar 28.


Cancer can provoke fatigue, sleep disturbances, and emotional distress. Hypnosis interventions have shown positive short-term effects on these symptoms. However, less is known about their long-term effects. This study assessed the short- and long-term effects of a group intervention combining self-care and self-hypnosis on these symptoms in posttreatment cancer patients. Ninety-five female cancer survivors were randomized to either a hypnosis group intervention or wait-list control. Results showed significant decreases in fatigue, sleep difficulties and emotional distress after intervention for the hypnosis group intervention in comparison to the wait-list control. Most of these positive effects were maintained at 1-year follow-up. Most participants received the hypnosis group intervention approximately 10.65 months after diagnosis, and it is possible that delivering the intervention earlier after diagnosis could have achieved a more robust impact. Further studies are needed to replicate these results in comparison to an active control condition and investigate the best time postdiagnosis for initiating the intervention.

Trial registration: ClinicalTrials.gov NCT03144154.

Keywords: Cancer; emotional distress; fatigue; hypnosis; self-care.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fatigue / etiology
  • Fatigue / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Hypnosis* / methods
  • Neoplasms* / complications
  • Neoplasms* / psychology
  • Neoplasms* / therapy
  • Psychological Distress*
  • Quality of Life / psychology
  • Self Care / methods
  • Sleep
  • Stress, Psychological / psychology
  • Stress, Psychological / therapy

Associated data

  • ClinicalTrials.gov/NCT03144154