Conservative treatment of head and neck lymphoma is not the only effective treatment: A retrospective analysis of 301 cases

Xutao Wen; Yuhua Hu; Yuan Liu; Zhengrui Li; Huaming Mai; Ling Zhang

doi:10.1016/j.oraloncology.2022.105828

Conservative treatment of head and neck lymphoma is not the only effective treatment: A retrospective analysis of 301 cases

Oral Oncol. 2022 May:128:105828. doi: 10.1016/j.oraloncology.2022.105828. Epub 2022 Mar 25.

Authors

Xutao Wen¹, Yuhua Hu², Yuan Liu³, Zhengrui Li³, Huaming Mai⁴, Ling Zhang⁵

Affiliations

¹ Department of Oral Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China; Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Clinical Research Center for Craniofacial Deformity, Nanning, People's Republic of China.
² Department of Oral Pathology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, People's Republic of China.
³ Department of Oral Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China.
⁴ Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Clinical Research Center for Craniofacial Deformity, Nanning, People's Republic of China. Electronic address: huamingmai@163.com.
⁵ Department of Oral Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China. Electronic address: topgun1128@163.com.

PMID: 35344710
DOI: 10.1016/j.oraloncology.2022.105828

Abstract

Objectives: To study the influence of different treatments on the prognosis of patients with head and neck lymphoma (HNL).

Materials and methods: A single center retrospective study was conducted on 301 patients with HNL diagnosed from 2015 to 2020, compare the disease-free survival rate of patients treated surgically or conservatively.

Results: For indolent non-Hodgkin's lymphoma (iNHL), there is no significant difference in the prolongation of disease-free survival time between surgery and conservative treatment (P > 0.05).

Conclusion: For iNHL especially in glands, we can adopt wide local excision without other therapy.

Keywords: Conservative treatment; Head and neck neoplasms; Lymphomas; Parotid gland; Surgery.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Conservative Treatment
Head and Neck Neoplasms* / therapy
Humans
Lymphoma*
Lymphoma, Non-Hodgkin* / diagnosis
Lymphoma, Non-Hodgkin* / therapy
Prognosis
Retrospective Studies