Survival study and factors associated with mortality in Chilean patients on peritoneal dialysis infected with SARS-CoV-2

Perit Dial Int. 2022 Sep;42(5):535-539. doi: 10.1177/08968608221087794. Epub 2022 Mar 30.


The Covid-19 pandemic has been responsible for millions of deaths worldwide. Patients with comorbidities- such as those on peritoneal dialysis (PD)- present higher morbidity and mortality than the general population. We prospectively evaluated all Chilean patients on PD (48 centres) and followed those who had Covid-19 from the beginning of the Covid-19 pandemic in Chile (March 2020) to January 2021 (start of vaccination campaign). We described demographic history, comorbidities, factors related to infection, need for hospitalisation and death due to Covid-19. During the study period, 106 adults on PD were infected by SARS-CoV-2, with a mean age of 53.1 (±16.3) and of which 53.9% were female. From that group, 54.8% required hospitalisation and 24.5% (n = 26) died due to Covid-19. Most of the patients (63.4%) were infected at home and 22.8% during hospitalisation for other reasons. There was a significant association for Covid-19 mortality with: being ≥60 years old, diabetes, time on PD ≥5 years, need for hospitalisation and hospital-acquired infection. At 90 days of follow-up, all deaths associated to Covid-19 occurred before 40 days. We conclude that patients on PD without Covid-19 vaccination have a high mortality and need for hospitalisation associated to Covid-19. To avoid this negative outcome, it is necessary to intensify strategies to avoid contagion, especially in those ≥60 years old, with diabetes and/or ≥5 years spent on PD.

Keywords: Covid-19; SARS-CoV-2; mortality; peritoneal dialysis; survival.

MeSH terms

  • Adult
  • COVID-19 Vaccines
  • COVID-19* / therapy
  • Chile / epidemiology
  • Diabetes Mellitus*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Peritoneal Dialysis*
  • SARS-CoV-2


  • COVID-19 Vaccines