Creating a User-Friendly and Open-Access Gene Expression Database for Comparing Embryonic Development and Regeneration in Nematostella vectensis

Methods Mol Biol. 2022:2450:649-662. doi: 10.1007/978-1-0716-2172-1_35.

Abstract

The sea anemone Nematostella vectensis has emerged as a powerful research model to understand at the gene regulatory network level, to what extend regeneration recapitulates embryonic development. Such comparison involves massive transcriptomic analysis, a routine approach for identifying differential gene expression. Here we present a workflow to build a user-friendly, mineable, and open-access database providing access to the scientific community to various RNAseq datasets.

Keywords: Cnidarian; Data mining; Database; Embryonic development; Nematostella vectensis; Open-access; RNAseq; Regeneration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Genetic
  • Embryonic Development / genetics
  • Gene Expression
  • Gene Expression Profiling
  • Sea Anemones*