Effectiveness and Harms of Colorectal Cancer Screening Strategies

Gastrointest Endosc Clin N Am. 2022 Apr;32(2):215-226. doi: 10.1016/j.giec.2021.12.002. Epub 2022 Feb 23.

Abstract

Colorectal cancer screening incorporates various testing modalities. Factors including effectiveness, harms, cost, screening interval, patient preferences, and test availability should be considered when determining which test to use. Fecal occult blood testing and endoscopic screening have the most robust evidence, while newer blood- and imaging-based techniques require further evaluation. In this review, we compare the effectiveness, harms, and costs of the various screening strategies.

Keywords: Adenoma; Colorectal cancer; Cost; Effectiveness; Endoscopy; Harm; Imaging; Screening.

Publication types

  • Review

MeSH terms

  • Colorectal Neoplasms* / prevention & control
  • Cost-Benefit Analysis
  • Early Detection of Cancer*
  • Humans
  • Mass Screening / methods
  • Occult Blood