Comparison of the Detection Rates of Different Diagnostic Methods for Primary Peripheral Lung Cancer

Lijuan Sun; Chao Qin; Qun Fu; Shuangmin Hu; Wenfei Zhao; Hongyun Li

doi:10.3389/fonc.2021.696239

Comparison of the Detection Rates of Different Diagnostic Methods for Primary Peripheral Lung Cancer

Front Oncol. 2022 Mar 17:11:696239. doi: 10.3389/fonc.2021.696239. eCollection 2021.

Authors

Lijuan Sun¹, Chao Qin¹, Qun Fu¹, Shuangmin Hu¹, Wenfei Zhao¹, Hongyun Li¹

Affiliation

¹ Department of Respiratory Medicine, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Abstract

Objective: The present study aims to compare the detection rates of different diagnostic methods for primary peripheral lung cancer (PPLC).

Methods: The detection rate and patient information were collected from a total of 359 cases of PPLC or a suspected diagnosis of lung cancer; among these, 186 cases were simultaneously treated with fibreoptic bronchoscopy, brush inspection and flush inspection, and 173 cases underwent a computed tomography (CT)-guided percutaneous lung biopsy (PNB). The positive detection rates of the different methods were compared.

Results: In the detection of peripheral lesions (diameter of <5 cm), the CT-PNB had the significantly highest detection rate, followed by the combined basic method (fibreoptic bronchoscopy + brushing + flushing). The independent use of the three basic sampling methods showed a significantly lower detection rate compared with the combined use.

Conclusion: In the diagnosis of peripheral lung cancer, the CT-PNB had the best detection rate; hence, it could be used in clinical practice for the diagnosis of such lesions.

Keywords: CT-guided; clinical research; fiberoptic bronchoscope; methods of sampling; peripheral lung cancer.