In acute ischemic stroke, EVT alone vs. IV alteplase plus EVT did not differ for functional outcome at 90 d

Ann Intern Med. 2022 Apr;175(4):JC42. doi: 10.7326/J22-0016. Epub 2022 Apr 5.

Abstract

LeCouffe NE, Kappelhof M, Treurniet KM, et al. A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med. 2021;385:1833-44. 34758251.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Comment

MeSH terms

  • Brain Ischemia* / drug therapy
  • Endovascular Procedures*
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Ischemic Stroke* / drug therapy
  • Stroke* / drug therapy
  • Thrombectomy
  • Tissue Plasminogen Activator / therapeutic use
  • Treatment Outcome

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator