Sequences closely related to an immunoglobulin gene promoter/enhancer element occur also upstream of other eukaryotic and of prokaryotic genes

Nucleic Acids Res. 1986 Nov 25;14(22):8819-27. doi: 10.1093/nar/14.22.8819.

Abstract

Decanucleotide sequences closely related to the TNATTTGCAT element which occurs upstream of the immunoglobulin genes and in the immunoglobulin gene enhancer were found also upstream of other eukaryotic and of prokaryotic genes. The possibility of evolutionary and functional relationships between the various transcriptional systems is discussed.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cells / immunology*
  • Enhancer Elements, Genetic*
  • Escherichia coli / genetics
  • Eukaryotic Cells / immunology*
  • Genes*
  • Genes, Regulator*
  • Humans
  • Immunoglobulins / genetics*
  • Oligodeoxyribonucleotides / genetics
  • Prokaryotic Cells / immunology*
  • Promoter Regions, Genetic*
  • Sequence Homology, Nucleic Acid
  • Species Specificity

Substances

  • Immunoglobulins
  • Oligodeoxyribonucleotides