Factors Associated with Risk of Perinatal Depressive Symptoms Among Puerto Rican Women with Hyperglycemia

Tiffany A Moore Simas; Katherine Leung; Emily Nuss; Michelle Marieni; Bess Marcus; Milagros C Rosal; Lisa Chasan-Taber

doi:10.1007/s10995-022-03429-y

Factors Associated with Risk of Perinatal Depressive Symptoms Among Puerto Rican Women with Hyperglycemia

Matern Child Health J. 2022 Aug;26(8):1741-1751. doi: 10.1007/s10995-022-03429-y. Epub 2022 Apr 6.

Authors

Tiffany A Moore Simas¹, Katherine Leung², Emily Nuss¹, Michelle Marieni¹, Bess Marcus³, Milagros C Rosal⁴, Lisa Chasan-Taber⁵

Affiliations

¹ Departments of Obstetrics & Gynecology, Pediatrics, Psychiatry and Population & Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
² Department of Obstetrics & Gynecology, University of Massachusetts Medical School, Worcester, MA, USA.
³ Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
⁴ Division of Preventive and Behavioral Medicine, Department of Population & Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
⁵ Department of Biostatistics & Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, 401 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003-9304, USA. LCT@umass.edu.

PMID: 35386031
DOI: 10.1007/s10995-022-03429-y

Abstract

Objectives: Rates of perinatal depression and pregnancy hyperglycemia are higher in Hispanic women as compared to non-Hispanic white women. In turn, depressive symptoms may reduce a woman's ability to engage in lifestyle changes that could reduce their subsequent diabetes risk.

Methods: We conducted a secondary analysis using data from Estudio Parto to evaluate sociodemographic, behavioral, psychosocial, and medical factors associated with perinatal depressive symptoms. Estudio Parto was a randomized controlled trial conducted in Western Massachusetts from 2013 to 17. Eligible participants had pregnancy hyperglycemia. The Edinburgh Postnatal Depression Scale (EPDS) was administered at 24-28 weeks gestation and at 6 weeks, 6 months, and 12 months postpartum. An EPDS cutpoint of 10 or greater defined the presence of depressive symptoms.

Results: In this sample of Puerto Rican women with pregnancy hyperglycemia, 32% and 27% showed prenatal and postpartum depressive symptoms, respectively. Among participants, 35.5% were diagnosed with GDM, 44.3% with isolated hyperglycemia, and 20.2% with impaired glucose tolerance. In multivariable models, being unmarried (OR 3.87; 95% CI 1.51-9.94), prenatal substance use (smoking or alcohol consumption; OR 2.96; 95% CI 1.41-6.18), and maternal age (1.11 for each year; 95% CI 1.04-1.18) were associated with higher odds of prenatal depressive symptoms. None of the risk factors were associated with subsequent postpartum depression in adjusted analyses.

Conclusions: Identifying factors associated with prenatal and postpartum depression in Puerto Rican women with pregnancy hyperglycemia can inform targeted lifestyle interventions in this at-risk group, increase the likely adoption of healthy lifestyle behaviors, and thereby work to address health disparities.

Clinicaltrials: gov NCT01679210; date of registration 08/07/2012.

Keywords: Diabetes prevention; Gestational diabetes; Hispanic; Postpartum depression; Prenatal depression.

Publication types

Randomized Controlled Trial

MeSH terms

Depression / diagnosis
Depression, Postpartum* / epidemiology
Depression, Postpartum* / psychology
Female
Hispanic or Latino
Humans
Hyperglycemia* / epidemiology
Postpartum Period
Pregnancy
Risk Factors

Associated data

ClinicalTrials.gov/NCT01679210

Abstract

Publication types

MeSH terms

Associated data

Grants and funding